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FABA 2Beta --- Functional Analysis By Association
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Genes Associated With Hs.1787 PLP1
Human Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)

Query Gene:

Hs.1787 PLP1 Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) GeneCard AmiGO Pubmed Google

Top Associated Genes:

  • Hs.567263 ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.121443 HOP Homeodomain-only protein GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.270978 MEST Mesoderm specific transcript homolog (mouse) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.371249 PTN Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.24587 EFS Embryonal Fyn-associated substrate GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.371727 SCNN1G Sodium channel, nonvoltage-gated 1, gamma GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.485616 DST Dystonin GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.235935 NOV Nephroblastoma overexpressed gene GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.138378 CASP4 Caspase 4, apoptosis-related cysteine peptidase GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.518236 SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.34780 DCX Doublecortex; lissencephaly, X-linked (doublecortin) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.143728 WASL Wiskott-Aldrich syndrome-like GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.373550 TGIF TGFB-induced factor (TALE family homeobox) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.567424 FAIM2 Fas apoptotic inhibitory molecule 2 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.289106 EMID1 EMI domain containing 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.525105 SLITRK6 SLIT and NTRK-like family, member 6 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.126667 EDG2 Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.468505 NRXN1 Neurexin 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.390736 CFLAR CASP8 and FADD-like apoptosis regulator GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.522099 PIGO Phosphatidylinositol glycan, class O GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.189920 PB1 Polybromo 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.159264 Clone 23948 mRNA sequence
  • Hs.368431 RUNX1T1 Runt-related transcription factor 1; translocated to, 1 (cyclin D-related) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.368255 KIAA0368 KIAA0368 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.210995 CA12 Carbonic anhydrase XII GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.114246 ZNF81 Zinc finger protein 81 (HFZ20) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.201776 PEG3 Paternally expressed 3 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.132553 SLC25A24 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.513987 SHMT1 Serine hydroxymethyltransferase 1 (soluble) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.497893 ENAH Enabled homolog (Drosophila) GeneCard AmiGO Pubmed Google Pubmed2 Google2

    Datasets Info:

    Normal Human Samples
    Dataset must contain at least one normal sample.
  • GDS1050 (13 samples) Valproic acid effect on theca cells (HG-U133A)
  • GDS1087 (30 samples) Normal tissues of diverse types (SHBA)
  • GDS1088 (11 samples) Normal tissues of diverse types (SHDP)
  • GDS1252 (26 samples) Idiopathic pulmonary fibrosis
  • GDS1304 (11 samples) Cigarette smoking effect on small airway epithelium
  • GDS1312 (10 samples) Squamous lung cancer
  • GDS1321 (24 samples) Barrett's metaplasia progression to adenocarcinoma
  • GDS261 (12 samples) Asthma exacerbatory factors
  • GDS484 (10 samples) Uterine fibroid and normal myometrial tissue
  • GDS505 (17 samples) Renal clear cell carcinoma (HG-U133A)
  • GDS511 (14 samples) Postmortem skeletal muscle
  • GDS533 (24 samples) Uterine smooth muscle tumor characterization
  • GDS651 (37 samples) Heart failure arising from different etiologies
  • GDS670 (15 samples) Emphysema lung tissue expression profiling
  • GDS707 (30 samples) Aging brain: frontal cortex expression profiles at various ages
  • GDS781 (10 samples) CD14 cells from granulocyte colony stimulating factor mobilized peripheral blood: expression profile
  • GDS963 (36 samples) Macular degeneration and dermal fibroblast response to sublethal oxidative stress

    Keys

  • Column: Dataset. Each dataset may contain tens to hundreds of array samples.
  • Row: Gene. The probe sequences for a gene may be different in different datasets.
  • Red color: Positive correlation, i.e., within the dataset (column) the query gene (in the title) and the gene represented in the row show positive correlations in their expressions.
  • Green color: Negative correlation, i.e., within the dataset (column) the query gene (in the title) and the gene represented in the row show negative correlations in their expressions.

    Questions about FABA?

  • Short answer: FABA is in silico two-hybrid software. It fishes for genes with correlated expressions and related functions.
  • Summary
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