Genes Associated With Sc.YLR337C VRP1
Budding Yeast END5|MDP2|YLR337W Proline-rich, actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP)

Query Gene: Sc.YLR337C VRP1 END5|MDP2|YLR337W Proline-rich, actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) GeneCard AmiGO Pubmed Google Top Associated Genes: Sc.YER096W SHC1 Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YMR240C CUS1 Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YBR278W DPB3 Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YDL201W TRM8 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YJL041W NSP1 Essential component of the nuclear pore complex, which mediates nuclear import and export GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YBR222C PCS60 FAT2 Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YDR382W RPP2B RPL45|YPA1 Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YMR290C HAS1 ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YLR189C ATG26 UGT51 UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YHR041C SRB2 HRS2|MED20 General transcription factor, subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YMR127C SAS2 Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YER179W DMC1 ISC2 Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YDL123W SNA4 Protein of unknown function, localized to the vacuolar outer membrane GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YKL208W CBT1 SOC1 Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YPL172C COX10 Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YOL077C BRX1 Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YJL089W SIP4 C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YER062C HOR2 GPP2 One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition GeneCard AmiGO Pubmed Google Pubmed2 Google2 Sc.YDR253C MET32 Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met31p GeneCard AmiGO Pubmed Google Pubmed2 Google2 Datasets Info: Budding Yeast Saccharomyce cerevisiae budding yeast datasets GDS1033 (6 samples) fhl1 and ifh1 deletion mutants GDS1103 (12 samples) leu3 mutant expression profiles GDS1205 (12 samples) Ssl1 mutant for a subunit of TFIIH response to methyl methanesulfonate GDS344 (11 samples) Chitin synthesis GDS354 (7 samples) Lithium response in yeast GDS362 (8 samples) Aging in yeast GDS608 (10 samples) Filamentous-form growth on solid media GDS750 (13 samples) HAC1 transcription and unfolded protein response GDS777 (24 samples) Nutrient limitation under aerobic and anaerobic conditions effect on gene expression GDS908 (6 samples) Xylose metabolism Keys Column: Dataset. Each dataset may contain tens to hundreds of array samples. Row: Gene. The probe sequences for a gene may be different in different datasets. Red color: Positive correlation, i.e., within the dataset (column) the query gene (in the title) and the gene represented in the row show positive correlations in their expressions. Green color: Negative correlation, i.e., within the dataset (column) the query gene (in the title) and the gene represented in the row show negative correlations in their expressions. Questions about FABA? Short answer: FABA is in silico two-hybrid software. It fishes for genes with correlated expressions and related functions. Summary User Manual (pdf) We need your help to improve FABA. Please subscribe and send us your feedback. Thanks!