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FABA 2Beta --- Functional Analysis By Association
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Genes Associated With Hs.1787 PLP1
Human Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)

Query Gene:

Hs.1787 PLP1 Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) GeneCard AmiGO Pubmed Google

Top Associated Genes:

  • Hs.567263 ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.49998 LDB3 LIM domain binding 3 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.407643 PCDH9 Protocadherin 9 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.432315 PDE4DIP Phosphodiesterase 4D interacting protein (myomegalin) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.495710 GPM6B Glycoprotein M6B GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.390567 FYN FYN oncogene related to SRC, FGR, YES GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.371249 PTN Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.121443 HOP Homeodomain-only protein GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.497723 MGC27165 Hypothetical protein MGC27165 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.503178 SPTBN1 Spectrin, beta, non-erythrocytic 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.160562 IGF1 Insulin-like growth factor 1 (somatomedin C) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.416769 PPM1B Protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.368431 RUNX1T1 Runt-related transcription factor 1; translocated to, 1 (cyclin D-related) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.288178 SSA2 TROVE domain family, member 2 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.484918 CMAH Cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.27695 MID1 Midline 1 (Opitz/BBB syndrome) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.129882 IMPG1 Interphotoreceptor matrix proteoglycan 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.485616 DST Dystonin GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.127562 HOXC11 Homeo box C11 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.235935 NOV Nephroblastoma overexpressed gene GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.270978 MEST Mesoderm specific transcript homolog (mouse) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.518236 SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.24587 EFS Embryonal Fyn-associated substrate GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.493275 TRIM31 Tripartite motif-containing 31 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.407856 SPINK1 Serine peptidase inhibitor, Kazal type 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.2133 RPE65 Retinal pigment epithelium-specific protein 65kDa GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.380325 FOLH1 Folate hydrolase (prostate-specific membrane antigen) 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.143728 WASL Wiskott-Aldrich syndrome-like GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.189920 PB1 Polybromo 1 GeneCard AmiGO Pubmed Google Pubmed2 Google2
  • Hs.155644 PAX2 Paired box gene 2 GeneCard AmiGO Pubmed Google Pubmed2 Google2

    Datasets Info:

    Breast Cancer & Normal Samples
    Datasets that are related to breast cancer or contain normal samples
  • GDS1050 (13 samples) Valproic acid effect on theca cells (HG-U133A)
  • GDS1087 (30 samples) Normal tissues of diverse types (SHBA)
  • GDS1088 (11 samples) Normal tissues of diverse types (SHDP)
  • GDS1094 (45 samples) Estrogen receptor alpha/beta heterodimer action in response to estrogen and tamoxifen
  • GDS1250 (8 samples) Atypical ductal hyperplasia and breast cancer
  • GDS1252 (26 samples) Idiopathic pulmonary fibrosis
  • GDS1304 (11 samples) Cigarette smoking effect on small airway epithelium
  • GDS1321 (24 samples) Barrett's metaplasia progression to adenocarcinoma
  • GDS1326 (12 samples) Breast cancer cells reexpressing estrogen receptor alpha response to 17beta-estradiol
  • GDS1329 (49 samples) Molecular apocrine breast tumors
  • GDS261 (12 samples) Asthma exacerbatory factors
  • GDS337 (20 samples) Telomerase overexpression
  • GDS360 (24 samples) Breast cancer and docetaxel treatment
  • GDS483 (9 samples) DACH1-responsive genes
  • GDS484 (10 samples) Uterine fibroid and normal myometrial tissue
  • GDS505 (17 samples) Renal clear cell carcinoma (HG-U133A)
  • GDS511 (14 samples) Postmortem skeletal muscle
  • GDS533 (24 samples) Uterine smooth muscle tumor characterization
  • GDS651 (37 samples) Heart failure arising from different etiologies
  • GDS670 (15 samples) Emphysema lung tissue expression profiling
  • GDS707 (30 samples) Aging brain: frontal cortex expression profiles at various ages
  • GDS781 (10 samples) CD14 cells from granulocyte colony stimulating factor mobilized peripheral blood: expression profile
  • GDS806 (60 samples) Estrogen positive breast cancer recurrence during tamoxifen therapy: whole tissue tumor
  • GDS807 (60 samples) Estrogen positive breast cancer recurrence during tamoxifen therapy: microdissected tumor
  • GDS881 (18 samples) Breast cancer and selective estrogen receptor modulators
  • GDS884 (20 samples) Estradiol effect on osteosarcoma cells expressing estrogen receptor alpha or beta: time course
  • GDS901 (12 samples) Estrogen receptor alpha L540Q mutation effect on gene induction by estradiol: time course
  • GDS963 (36 samples) Macular degeneration and dermal fibroblast response to sublethal oxidative stress

    Keys

  • Column: Dataset. Each dataset may contain tens to hundreds of array samples.
  • Row: Gene. The probe sequences for a gene may be different in different datasets.
  • Red color: Positive correlation, i.e., within the dataset (column) the query gene (in the title) and the gene represented in the row show positive correlations in their expressions.
  • Green color: Negative correlation, i.e., within the dataset (column) the query gene (in the title) and the gene represented in the row show negative correlations in their expressions.

    Questions about FABA?

  • Short answer: FABA is in silico two-hybrid software. It fishes for genes with correlated expressions and related functions.
  • Summary
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