Online

Download

Store

Contact

About

FABA 2.01^Beta --- Functional Analysis By Association
FABA home Browse Tell a colleague Subscribe Login Support

Disease-related genes

Serologically defined breast cancer antigen NY-BR-40

Similar to Galectin-3 binding protein precursor (Lectin galactoside-binding soluble 3 binding protein) (Mac-2 binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K)

RAB12, member RAS oncogene family

Down syndrome related transcript mRNA sequence

Transcribed locus, strongly similar to XP_507970.1 PREDICTED: similar to Hermansky-Pudlak syndrome 1 protein isoform a; Hermansky-Pudlak syndrome gene; Hermansky-Pudlak syndrome type 1 [Pan troglodytes]

Colorectal cancer-related mRNA sequence

IgV lambda [human, chronic lymphocytic leukemia case P87, mRNA Partial Mutant, 237 nt]

TCR V alpha 14.1/J alpha 32/C alpha =melanoma antigen-specific T-cell receptor alpha chain {V-J-C junction, alternatively spliced, clone TIL C10-1} [human, CD8+ tumor-infiltrating lymphocytes, mRNA Partial, 108 nt]

Similar to 60S ribosomal protein L10 (QM protein) (Tumor suppressor QM) (Laminin receptor homolog)

Similar to proline dehydrogenase (oxidase) 1; tumor protein p53 inducible protein 6; p53 induced protein; proline oxidase 2; proline dehydrogenase (proline oxidase )

(clone B3B3E13) Huntington's disease candidate region mRNA fragment

Transcribed locus, strongly similar to NP_031860.1 Down syndrome critical region protein A [Mus musculus]

Transcribed locus, strongly similar to XP_132006.4 PREDICTED: Wolf-Hirschhorn syndrome candidate 1 isoform 1 [Mus musculus]

Tumor necrosis factor receptor superfamily, member 1b

Retroviral-like c-Ha-ras proto-oncogene mRNA, partial sequence

Transcribed locus, strongly similar to NP_057254.1 T-cell leukemia, homeobox 2 isoform 1; homeo box 11-like 1 [Homo sapiens]

Transcribed locus, strongly similar to XP_620250.1 PREDICTED: similar to tumor suppressor candidate 5 [Mus musculus]

Transcribed locus, strongly similar to XP_543384.2 PREDICTED: similar to transmembrane protein induced by tumor necrosis factor alpha [Canis familiaris]

Transcribed locus, strongly similar to NP_733751.1 myeloid/lymphoid or mixed-lineage leukemia 3; myeloid/lymphoid or mixed-lineage leukemia3; ALR-like protein [Homo sapiens]

Transcribed locus, weakly similar to XP_518443.1 PREDICTED: pim-1 oncogene [Pan troglodytes]

Transcribed locus, moderately similar to NP_067053.1 myeloid/lymphoid or mixed-lineage leukemia 3; myeloid/lymphoid or mixed-lineage leukemia3; ALR-like protein [Homo sapiens]

Transcribed locus, strongly similar to NP_033418.1 T-cell leukemia, homeobox 2 [Mus musculus]

Transcribed locus, strongly similar to NP_036462.1 MYST histone acetyltransferase (monocytic leukemia) 4; histone acetyltransferase; monocytic leukemia zinc finger protein-related factor [Homo sapiens]

ABC1 Amplified in breast cancer 1

ABL1 V-abl Abelson murine leukemia viral oncogene homolog 1

Abl1_mapped V-abl Abelson murine leukemia viral oncogene homolog 1 (mapped)

ABL2 V-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

ADAM17 ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)

Adam17 A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)

AF1Q Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11

AGL Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III)

Agl_predicted Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) (predicted)

AKT1 V-akt murine thymoma viral oncogene homolog 1

Akt1 Thymoma viral proto-oncogene 1

AKT2 V-akt murine thymoma viral oncogene homolog 2

AKT3 V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

Akt3 Thymoma viral proto-oncogene 3

ALG6 Glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease

ALMS1 Alstrom syndrome 1

AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region, gene 1

AMPH Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)

APJ1 Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion

APP Amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)

AR Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)

ARAF V-raf murine sarcoma 3611 viral oncogene homolog

Araf1 V-raf oncogene homolog 1 (murine sarcoma 3611 virus)

ARMET Arginine-rich, mutated in early stage tumors

Armet_predicted Arginine-rich, mutated in early stage tumors (predicted)

ARTS-1 Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

Arts1 Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

ARVCF Armadillo repeat gene deletes in velocardiofacial syndrome

Arvcf_predicted Armadillo repeat gene deleted in velo-cardio-facial syndrome (predicted)

ASPA Aspartoacylase (Canavan disease)

ATP7A ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)

ATRX Alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

Atrx Alpha thalassemia/mental retardation syndrome X-linked homolog (human)

AVP Arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal)

AVPR2 Arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)

BAALC Brain and acute leukemia, cytoplasmic

Baalc Brain and acute leukemia, cytoplasmic

BBS1 Bardet-Biedl syndrome 1

BBS2 Bardet-Biedl syndrome 2

Bbs2 Bardet-Biedl syndrome 2 homolog (human)

BBS4 Bardet-Biedl syndrome 4

BBS5 Bardet-Biedl syndrome 5

BBS7 Bardet-Biedl syndrome 7

Bbs7 Bardet-Biedl syndrome 7

BCAR1 Breast cancer anti-estrogen resistance 1

Bcar1 Breast cancer anti-estrogen resistance 1

BCAR3 Breast cancer anti-estrogen resistance 3

Bcar3_predicted Breast cancer anti-estrogen resistance 3 (predicted)

BCKDHB Branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)

Bcl2 B-cell leukemia/lymphoma 2

Bcl2a1 B-cell leukemia/lymphoma 2 related protein A1

Bcl3_predicted B-cell leukemia/lymphoma 3 (predicted)

Bcl6_predicted B-cell leukemia/lymphoma 6 (predicted)

BCMP11 Breast cancer membrane protein 11

BLCAP Bladder cancer associated protein

Blcap Bladder cancer associated protein homolog (human)

Bles03 Basophilic leukemia expressed protein BLES03

BLM Bloom syndrome

Bmyc_mapped Brain expressed myelocytomatosis oncogene (mapped)

Boc_predicted Biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein (predicted)

BPH1 Protein homologous to human Chediak-Higashi syndrome protein and murine beige gene, which are implicated in disease syndromes due to defective lysosomal trafficking

BRAF V-raf murine sarcoma viral oncogene homolog B1

BRCA1 Breast cancer 1, early onset

BRCA2 Breast cancer 2, early onset

Brca2 Breast cancer 2

BRMS1 Breast cancer metastasis suppressor 1

Brms1 Breast cancer metastasis-suppressor 1

BRMS1L Breast cancer metastasis-suppressor 1-like

Brms1l_predicted Breast cancer metastasis-suppressor 1-like (predicted)

C1QTNF1 C1q and tumor necrosis factor related protein 1

C1qtnf1 C1q and tumor necrosis factor related protein 1

C1QTNF2 C1q and tumor necrosis factor related protein 2

C1QTNF3 C1q and tumor necrosis factor related protein 3

C1qtnf3_predicted C1q and tumor necrosis factor related protein 3 (predicted)

C1QTNF4 C1q and tumor necrosis factor related protein 4

C1qtnf4_predicted C1q and tumor necrosis factor related protein 4 (predicted)

C1QTNF5 C1q and tumor necrosis factor related protein 5

C1QTNF6 C1q and tumor necrosis factor related protein 6

C1qtnf6 C1q and tumor necrosis factor related protein 6

C1QTNF7 C1q and tumor necrosis factor related protein 7

CASC1 Cancer susceptibility candidate 1

Casc1_predicted Cancer susceptibility candidate 1 (predicted)

CASC2 Cancer susceptibility candidate 2

CASC3 Cancer susceptibility candidate 3

CCC2 Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases

CD40LG CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)

CDC45 SLD4 DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes

Cdon Cell adhesion molecule-related/down-regulated by oncogenes

CECR1 Cat eye syndrome chromosome region, candidate 1

CECR2 Cat eye syndrome chromosome region, candidate 2

CECR5 Cat eye syndrome chromosome region, candidate 5

Cecr5_predicted Cat eye syndrome chromosome region, candidate 5 (predicted)

CECR6 Cat eye syndrome chromosome region, candidate 6

CECR7 Cat eye syndrome chromosome region, candidate 7

CHL1 CTF1|LPA9 Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p

CIAS1 Cold autoinflammatory syndrome 1

Ckn1_predicted Cockayne syndrome 1 (classical) (predicted)

CLCN1 Chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant)

CLCN5 Chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease)

CLDN5 Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome)

CLN3 Ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

Cohh1_predicted Cohen syndrome homolog 1 (predicted)

COL3A1 Collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)

COL4A5 Collagen, type IV, alpha 5 (Alport syndrome)

CREBBP CREB binding protein (Rubinstein-Taybi syndrome)

CRK V-crk sarcoma virus CT10 oncogene homolog (avian)

Crk V-crk sarcoma virus CT10 oncogene homolog (avian)

CRKL V-crk sarcoma virus CT10 oncogene homolog (avian)-like

CSF1R Colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog

CTAG1B Cancer/testis antigen 1B

CTAG2 Cancer/testis antigen 2

CYBB Cytochrome b-245, beta polypeptide (chronic granulomatous disease)

CYLD Cylindromatosis (turban tumor syndrome)

DBC1 Deleted in bladder cancer 1

Dbccr1 Deleted in bladder cancer chromosome region candidate 1 (human)

DEC1 Deleted in esophageal cancer 1

DEK DEK oncogene (DNA binding)

Dek DEK oncogene (DNA binding)

DGCR14 DiGeorge syndrome critical region gene 13

Dgcr14 DiGeorge syndrome critical region gene 14

DGCR2 DiGeorge syndrome critical region gene 2

DGCR5 DiGeorge syndrome critical region gene 5 (non-coding)

DGCR6 DiGeorge syndrome critical region gene 6

DGCR6L DiGeorge syndrome critical region gene 6-like

Dgcr6_predicted DiGeorge syndrome critical region gene 6 (predicted)

DGCR8 DiGeorge syndrome critical region gene 8

Dgcr8_predicted DiGeorge syndrome critical region gene 8 (predicted)

DGCR9 DiGeorge syndrome critical region gene 9

DLC1 Deleted in liver cancer 1

Dlc1 Deleted in liver cancer 1

DLEC1 Deleted in lung and esophageal cancer 1

DLEU1 Deleted in lymphocytic leukemia, 1

DLEU2 Deleted in lymphocytic leukemia, 2

DMBT1 Deleted in malignant brain tumors 1

Dmbt1 Deleted in malignant brain tumors 1

DOC1 Downregulated in ovarian cancer 1

DPH2L1 Candidate tumor suppressor in ovarian cancer 2

DSCAM Down syndrome cell adhesion molecule

Dscam Down syndrome cell adhesion molecule

Dscaml1_predicted Down syndrome cell adhesion molecule-like 1 (predicted)

DSCR1 Down syndrome critical region gene 1

Dscr1 Down syndrome critical region homolog 1 (human)

DSCR1L1 Down syndrome critical region gene 1-like 1

Dscr1l1 Down syndrome critical region gene 1-like 1

DSCR1L2 Down syndrome critical region gene 1-like 2

DSCR2 Down syndrome critical region gene 2

Dscr2_predicted Down syndrome critical region gene 2 (predicted)

DSCR3 Down syndrome critical region gene 3

DSCR4 Down syndrome critical region gene 4

Dscr5_predicted Down syndrome critical region gene 5 (predicted)

DSCR6 Down syndrome critical region gene 6

Dscr6_predicted Down syndrome critical region gene 6 (predicted)

DSCR8 Down syndrome critical region gene 8

DSCR9 Down syndrome critical region gene 9

ECT2 Epithelial cell transforming sequence 2 oncogene

EGFR Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)

ELK1 ELK1, member of ETS oncogene family

Elk3_predicted ELK3, member of ETS oncogene family (predicted)

ELN Elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)

ENG Endoglin (Osler-Rendu-Weber syndrome 1)

EPM2A Epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)

ERBB2 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Erbb2 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Erbb3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

ERBB4 V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Erbb4 V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

ERCC5 Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))

ERG V-ets erythroblastosis virus E26 oncogene like (avian)

Erg V-ets erythroblastosis virus E26 oncogene like (avian)

ERS1 Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains

ETS1 V-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

Ets1 V-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

ETS2 V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

ETV6 Ets variant gene 6 (TEL oncogene)

ETV7 Ets variant gene 7 (TEL2 oncogene)

EVC Ellis van Creveld syndrome

EVC2 Ellis van Creveld syndrome 2 (limbin)

F9 Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)

FAT FAT tumor suppressor homolog 1 (Drosophila)

FAT2 FAT tumor suppressor homolog 2 (Drosophila)

FAT3 FAT tumor suppressor homolog 3 (Drosophila)

Fat3 FAT tumor suppressor homolog 3 (Drosophila)

FAT4 FAT tumor suppressor homolog 4 (Drosophila)

Fath Fat tumor suppressor homolog (Drosophila)

FBN1 Fibrillin 1 (Marfan syndrome)

FCY1 yCD Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)

FES Feline sarcoma oncogene

FEV FEV (ETS oncogene family)

Fev FEV (ETS oncogene family)

FGF3 Fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)

FGF4 Fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)

FGFR1 Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)

FGFR1OP FGFR1 oncogene partner

FGFR1OP2 FGFR1 oncogene partner 2

FGFR2 Fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)

FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog

Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog

FLI1 Friend leukemia virus integration 1

Fli1 Friend leukemia integration 1

FLJ11712 Deleted in leukemia 8 protein

FLJ23467 Tumor necrosis factor, alpha-induced protein 8-like 2

FLJ32915 Hydrolethalus syndrome 1

FLJ34283 Parkinson disease 7 domain containing 1

FLVCR Feline leukemia virus subgroup C cellular receptor

Fmr1 Fragile X mental retardation syndrome 1 homolog

FOS V-fos FBJ murine osteosarcoma viral oncogene homolog

Fos FBJ murine osteosarcoma viral oncogene homolog

FOSB FBJ murine osteosarcoma viral oncogene homolog B

Fosb FBJ osteosarcoma oncogene B

FRAS1 Fraser syndrome 1

Fras1_predicted Fraser syndrome 1 (predicted)

FYN FYN oncogene related to SRC, FGR, YES

Fyn Fyn proto-oncogene

G6PC Glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)

GAA Glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)

GALNS Galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA)

GBE1 Glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)

GCK Glucokinase (hexokinase 4, maturity onset diabetes of the young 2)

GDDR Down-regulated in gastric cancer GDDR

GLI1 Glioma-associated oncogene homolog 1 (zinc finger protein)

GLI3 GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)

GLRA1 Glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)

GLTSCR1 Glioma tumor suppressor candidate region gene 1

GLTSCR2 Glioma tumor suppressor candidate region gene 2

Gltscr2 Glioma tumor suppressor candidate region gene 2

GNS Glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID)

HD Huntingtin (Huntington disease)

Hdh Huntington disease gene homolog

HIC2 Hypermethylated in cancer 2

HLC-8 Lung cancer-related protein 8

HLCS Holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)

HLF Hepatic leukemia factor

Hlf Hepatic leukemia factor

HNT2 APH1 Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins

HOM-TES-103 HOM-TES-103 tumor antigen-like

HPRT1 Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)

HPS1 Hermansky-Pudlak syndrome 1

Hps1 Hermansky-Pudlak syndrome 1 homolog (human)

HPS3 Hermansky-Pudlak syndrome 3

HPS4 Hermansky-Pudlak syndrome 4

Hps4_predicted Hermansky-Pudlak syndrome 4 (predicted)

HPS5 Hermansky-Pudlak syndrome 5

HPS6 Hermansky-Pudlak syndrome 6

HPT1 BRA6|HGPRTase|HPRT Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrom

HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog

Hrpt2 Hyperparathyroidism 2 (with jaw tumor)

HSP31 Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp32p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer

HSP32 Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease

HSP33 Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp32p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease

HTLF Human T-cell leukemia virus enhancer factor

IDS Iduronate 2-sulfatase (Hunter syndrome)

JAG1 Jagged 1 (Alagille syndrome)

JUN V-jun sarcoma virus 17 oncogene homolog (avian)

Jun Jun oncogene

JUNB Jun B proto-oncogene

Junb Jun-B oncogene

JUND Jun D proto-oncogene

KAL1 Kallmann syndrome 1 sequence

Kist Kinase interacting with leukemia-associated gene

KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Kit V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

KRAS2 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Kras2 Kirsten rat sarcoma viral oncogene homologue 2 (active)

LAS17 BEE1 Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments; localizes with the Arp2/3 complex to actin patches; homolog of the human Wiskott-Aldrich syndrome protein (WASP)

LATS1 LATS, large tumor suppressor, homolog 1 (Drosophila)

LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila)

LCN2 Lipocalin 2 (oncogene 24p3)

LDOC1 Leucine zipper, down-regulated in cancer 1

LDOC1L Leucine zipper, down-regulated in cancer 1-like

LEU5 Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized

Lif Leukemia inhibitory factor

LIFR Leukemia inhibitory factor receptor

Lifr Leukemia inhibitory factor receptor

LIPA Lipase A, lysosomal acid, cholesterol esterase (Wolman disease)

LOC288913 Similar to LEYDIG CELL TUMOR 10 KD PROTEIN

LOC311191 Similar to colonic and hepatic tumor over-expressed protein isoform a

LOC313535 Similar to prion protein interacting protein 1

LOC368084 Similar to Putative methyltransferase HUSSY-03 (Williams-Beuren syndrome chromosome region 22 protein homolog)

LOC498035 Similar to cylindromatosis (turban tumor syndrome)

LOC498191 Similar to RAB35, member RAS oncogene family

LOC498968 Similar to mammary tumor receptor 2 isoform-like protein

LOC499760 Similar to serologically defined colon cancer antigen 3

LRP1B Low density lipoprotein-related protein 1B (deleted in tumors)

LSB1 Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization

LSB3 YFR024C Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization

LSB5 Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization

LSB6 Phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization

LYL1 Lymphoblastic leukemia derived sequence 1

Lyl1 Lymphoblastic leukemia derived sequence 1

LYN V-yes-1 Yamaguchi sarcoma viral related oncogene homolog

Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

LZTS1 Leucine zipper, putative tumor suppressor 1

Lzts1 Leucine zipper, putative tumor suppressor 1

LZTS2 Leucine zipper, putative tumor suppressor 2

Lzts2 Leucine zipper, putative tumor suppressor 2

MAF V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

Maf V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog (c-maf)

MAFB V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Mafb V-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

MAFF V-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

MAFG V-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)

Mafg V-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)

MAFK V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)

Mafk V-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)

MAS1 MAS1 oncogene

Mas1 MAS1 oncogene

MCC Mutated in colorectal cancers

MCL1 Myeloid cell leukemia sequence 1 (BCL2-related)

Mcl1 Myeloid cell leukemia sequence 1

MDM38 MKH1 Mitochondrial inner membrane protein, required for K+/H+ exchange and for normal mitochondrial morphology and inheritance; associates with mitochondrial ribosomes; human ortholog Letm1 is implicated in Wolf-Hirschhorn syndrome

MDS1 Myelodysplasia syndrome 1

MECP2 Methyl CpG binding protein 2 (Rett syndrome)

MERTK C-mer proto-oncogene tyrosine kinase

Mertk C-mer proto-oncogene tyrosine kinase

MET Met proto-oncogene (hepatocyte growth factor receptor)

Met Met proto-oncogene

MGC16824 Esophageal cancer associated protein

MGC17791 Tumor necrosis factor, alpha-induced protein 8-like 1

MID1 Midline 1 (Opitz/BBB syndrome)

MIG1 CAT4|SSN1|TDS22 Transcription factor involved in glucose repression; C2H2 zinc finger protein similar to mammalian Egr and Wilms tumor proteins

MKKS McKusick-Kaufman syndrome

Mkks McKusick-Kaufman syndrome protein

MKL1 Megakaryoblastic leukemia (translocation) 1

Mkl1_predicted Megakaryoblastic leukemia (translocation) 1 (predicted)

MLF1 Myeloid leukemia factor 1

Mlf1_predicted Myeloid leukemia factor 1 (predicted)

MLF2 Myeloid leukemia factor 2

Mlf2_predicted Myeloid leukemia factor 2 (predicted)

MLH1 MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)

MLH1 PMS2 Protein required for mismatch repair in mitosis and meiosis, postmeiotic segregation, and spore viability; forms a complex with Pms1p and Msh2p to repair mismatched DNA; human homolog is associated with hereditary non-polyposis colon cancer

MLL Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

MLL2 Myeloid/lymphoid or mixed-lineage leukemia 2

MLL3 Myeloid/lymphoid or mixed-lineage leukemia 3

MLL4 Myeloid/lymphoid or mixed-lineage leukemia 4

MLL5 Myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

Mll5 Myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

MLLT1 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1

MLLT10 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10

Mllt10 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10

Mllt2_predicted Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2 (predicted)

MLLT3 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

Mllt3 Myeloid/lymphoid or mixed-lineage leukemia,translocated to, 3 (trithorax homolog, Drosophila)

MLLT4 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

MLLT6 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

MLLT7 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7

MOS V-mos Moloney murine sarcoma viral oncogene homolog

MOV10 Mov10, Moloney leukemia virus 10, homolog (mouse)

MOV10L1 Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)

MPL Myeloproliferative leukemia virus oncogene

Mpv17l_predicted Mpv17 transgene, kidney disease mutant-like (predicted)

MRAS Muscle RAS oncogene homolog

MSH2 MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)

MTUS1 Mitochondrial tumor suppressor 1

Mtus1 Mitochondrial tumor suppressor 1

Mtvr2 Mammary tumor virus receptor 2

MYB V-myb myeloblastosis viral oncogene homolog (avian)

MYBL1 V-myb myeloblastosis viral oncogene homolog (avian)-like 1

Mybl1_predicted Myeloblastosis oncogene-like 1 (predicted)

MYBL2 V-myb myeloblastosis viral oncogene homolog (avian)-like 2

Mybl2_predicted Myeloblastosis oncogene-like 2 (predicted)

MYC V-myc myelocytomatosis viral oncogene homolog (avian)

Myc Myelocytomatosis viral oncogene homolog (avian)

MYCL1 V-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)

MYCN V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

MYCNOS V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand

Mycn_mapped V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (mapped)

Mycs Myc-like oncogene, s-myc protein

MYST3 MYST histone acetyltransferase (monocytic leukemia) 3

MYST4 MYST histone acetyltransferase (monocytic leukemia) 4

NAGLU N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB)

NAS6 Regulatory, non-ATPase subunit of the 26S proteasome; homolog of the human oncoprotein gankyrin, which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4/6

NBL1 Neuroblastoma, suppression of tumorigenicity 1

Nbl1 Neuroblastoma, suppression of tumorigenicity 1

NCF1 Neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1)

NCF2 Neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)

NDP Norrie disease (pseudoglioma)

NEW1 ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation, susceptibility to [PSI+] prion induction and aggregation of a fragment of the human Machado-Joseph Disease protein

NF1 Neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)

NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)

NIPA2 Non imprinted in Prader-Willi/Angelman syndrome 2

NIT2 Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member

NIT3 Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member

NKTR Natural killer-tumor recognition sequence

NPC1 Niemann-Pick disease, type C1

NPC1L1 NPC1 (Niemann-Pick disease, type C1, gene)-like 1

NPC2 Niemann-Pick disease, type C2

NPC2 Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes

NRAS Neuroblastoma RAS viral (v-ras) oncogene homolog

Nras Neuroblastoma ras oncogene

NYD-SP25 Tumor protein D52-like 3

OCRL Oculocerebrorenal syndrome of Lowe

OFD1 Oral-facial-digital syndrome 1

ORT1 ARG11 Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome

OTU2 Putative protein of unknown function, member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

PANK2 Pantothenate kinase 2 (Hallervorden-Spatz syndrome)

Pank2_predicted Pantothenate kinase 2 (Hallervorden-Spatz syndrome) (predicted)

PARK2 Parkinson disease (autosomal recessive, juvenile) 2, parkin

PARK7 Parkinson disease (autosomal recessive, early onset) 7

PAX3 Paired box gene 3 (Waardenburg syndrome 1)

PBOV1 Prostate and breast cancer overexpressed 1

PBX1 Pre-B-cell leukemia transcription factor 1

Pbx1_predicted Pre-B-cell leukemia transcription factor 1 (predicted)

PBX2 Pre-B-cell leukemia transcription factor 2

Pbx2 Pre-B-cell leukemia transcription factor 2

PBX3 Pre-B-cell leukemia transcription factor 3

Pbx3_predicted Pre B-cell leukemia transcription factor 3 (predicted)

PBX4 Pre-B-cell leukemia transcription factor 4

PBXIP1 Pre-B-cell leukemia transcription factor interacting protein 1

PDGFB Platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

PHO23 Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)

PIM1 Pim-1 oncogene

PIM2 Pim-2 oncogene

PIM3 Pim-3 oncogene

PIN2 Protein that induces appearance of [PIN+] prion when overproduced

PIN3 LSB2 Protein that induces appearance of [PIN+] prion when overproduced

PKD1 Polycystic kidney disease 1 (autosomal dominant)

Pkd1 Polycystic kidney disease 1 homolog

PKD1L1 Polycystic kidney disease 1 like 1

PKD2 Polycystic kidney disease 2 (autosomal dominant)

PKD2L1 Polycystic kidney disease 2-like 1

PKD2L2 Polycystic kidney disease 2-like 2

PKDREJ Polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)-like

PKHD1 Polycystic kidney and hepatic disease 1 (autosomal recessive)

PKHD1L1 Polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1

PKP1 Plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

PLP1 Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)

PML Promyelocytic leukemia

PMR1 BSD1|LDB1 High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease

Prg4_predicted Proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome) (predicted)

PRND Prion protein 2 (dublet)

PRNP Prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)

Prnp Prion protein

PRNPIP Prion protein interacting protein

PSAP Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)

PSEN1 Presenilin 1 (Alzheimer disease 3)

PSEN2 Presenilin 2 (Alzheimer disease 4)

PSY2 Nuclear protein of unknown function; deletion results in sensitivity to anticancer drugs oxaliplatin and cisplatin, but not mitomycin C; deletion is synthetically lethal with a chitin synthase (CHS1) null mutant

PSY3 Protein of unknown function; deletion results in a mutator phenotype suggesting a role for this protein as a mutational suppressor; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C

PTEN Phosphatase and tensin homolog (mutated in multiple advanced cancers 1)

PTENP1 Phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1

PTOV1 Prostate tumor overexpressed gene 1

Ptov1 Prostate tumor over expressed gene 1

PTPN11 Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)

PTTG1 Pituitary tumor-transforming 1

Pttg1 Pituitary tumor-transforming 1

PTTG1IP Pituitary tumor-transforming 1 interacting protein

Pttg1ip Pituitary tumor-transforming 1 interacting protein

PTTG2 Pituitary tumor-transforming 2

PVT1 Pvt1 oncogene homolog, MYC activator (mouse)

PXMP3 Peroxisomal membrane protein 3, 35kDa (Zellweger syndrome)

PYGL Phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI)

PYGM Phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V)

Rab1 RAB1, member RAS oncogene family

RAB10 RAB10, member RAS oncogene family

Rab10 RAB10, member RAS oncogene family

RAB11A RAB11A, member RAS oncogene family

Rab11a RAB11a, member RAS oncogene family

RAB11B RAB11B, member RAS oncogene family

Rab11b RAB11B, member RAS oncogene family

Rab12 RAB12, member RAS oncogene family

RAB13 RAB13, member RAS oncogene family

Rab13 RAB13, member RAS oncogene family

RAB14 RAB14, member RAS oncogene family

Rab14 RAB14, member RAS oncogene family

RAB17 RAB17, member RAS oncogene family

RAB18 RAB18, member RAS oncogene family

RAB1A RAB1A, member RAS oncogene family

RAB1B RAB1B, member RAS oncogene family

RAB2 RAB2, member RAS oncogene family

Rab2 RAB2, member RAS oncogene family

RAB20 RAB20, member RAS oncogene family

RAB21 RAB21, member RAS oncogene family

Rab21 RAB21, member RAS oncogene family

RAB22A RAB22A, member RAS oncogene family

RAB23 RAB23, member RAS oncogene family

RAB24 RAB24, member RAS oncogene family

RAB25 RAB25, member RAS oncogene family

Rab25_predicted RAB25, member RAS oncogene family (predicted)

RAB26 RAB26, member RAS oncogene family

Rab26 RAB26, member RAS oncogene family

RAB27A RAB27A, member RAS oncogene family

RAB27B RAB27B, member RAS oncogene family

RAB28 RAB28, member RAS oncogene family

Rab28 RAB28, member RAS oncogene family

RAB2B RAB2B, member RAS oncogene family

Rab2l RAB2, member RAS oncogene family-like

RAB30 RAB30, member RAS oncogene family

RAB31 RAB31, member RAS oncogene family

RAB32 RAB32, member RAS oncogene family

RAB33A RAB33A, member RAS oncogene family

RAB33B RAB33B, member RAS oncogene family

RAB34 RAB34, member RAS oncogene family

RAB35 RAB35, member RAS oncogene family

RAB36 RAB36, member RAS oncogene family

RAB37 RAB37, member RAS oncogene family

RAB38 RAB38, member RAS oncogene family

Rab38 Rab38, member of RAS oncogene family

RAB39B RAB39B, member RAS oncogene family

Rab39_predicted RAB39, member RAS oncogene family (predicted)

RAB3A RAB3A, member RAS oncogene family

Rab3a RAB3A, member RAS oncogene family

RAB3B RAB3B, member RAS oncogene family

Rab3b RAB3B, member RAS oncogene family

RAB3C RAB3C, member RAS oncogene family

Rab3c RAB3C, member RAS oncogene family

RAB3D RAB3D, member RAS oncogene family

RAB40A RAB40A, member RAS oncogene family

RAB40B RAB40B, member RAS oncogene family

RAB40C RAB40C, member RAS oncogene family

RAB43 RAB43, member RAS oncogene family

RAB4A RAB4A, member RAS oncogene family

Rab4a RAB4A, member RAS oncogene family

RAB4B RAB4B, member RAS oncogene family

Rab4b RAB4B, member RAS oncogene family

RAB5A RAB5A, member RAS oncogene family

Rab5a RAB5A, member RAS oncogene family

RAB5B RAB5B, member RAS oncogene family

Rab5b_predicted RAB5B, member RAS oncogene family (predicted)

RAB5C RAB5C, member RAS oncogene family

Rab5c_predicted RAB5C, member RAS oncogene family (predicted)

RAB6A RAB6A, member RAS oncogene family

RAB6B RAB6B, member RAS oncogene family

Rab6b_predicted RAB6B, member RAS oncogene family (predicted)

RAB6C RAB6C, member RAS oncogene family

RAB7 RAB7, member RAS oncogene family

Rab7 RAB7, member RAS oncogene family

RAB7B RAB7B, member RAS oncogene family

RAB7L1 RAB7, member RAS oncogene family-like 1

Rab7l1 RAB7, member RAS oncogene family-like 1

RAB8A RAB8A, member RAS oncogene family

RAB8B RAB8B, member RAS oncogene family

Rab8b RAB8B, member RAS oncogene family

Rab9 RAB9, member RAS oncogene family

RAB9A RAB9A, member RAS oncogene family

RAB9B RAB9B, member RAS oncogene family

RAB9P1 RAB9, member RAS oncogene family, pseudogene 1

RABL2A RAB, member of RAS oncogene family-like 2A

RABL2B RAB, member of RAS oncogene family-like 2B

RABL3 RAB, member of RAS oncogene family-like 3

Rabl3_predicted RAB, member of RAS oncogene family-like 3 (predicted)

RABL4 RAB, member of RAS oncogene family-like 4

Rabl4_predicted RAB, member of RAS oncogene family-like 4 (predicted)

RABL5 RAB, member RAS oncogene family-like 5

Rabl5 RAB, member of RAS oncogene family-like 5

RAF1 V-raf-1 murine leukemia viral oncogene homolog 1

Raf1 V-raf-1 murine leukemia viral oncogene homolog 1

RAGE Renal tumor antigen

RALA V-ral simian leukemia viral oncogene homolog A (ras related)

Rala V-ral simian leukemia viral oncogene homolog A (ras related)

RALB V-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)

Ralb V-ral simian leukemia viral oncogene homolog B

RAN RAN, member RAS oncogene family

Ran RAN, member RAS oncogene family

RAP1A RAP1A, member of RAS oncogene family

RAP1B RAP1B, member of RAS oncogene family

RAP2A RAP2A, member of RAS oncogene family

RAP2B RAP2B, member of RAS oncogene family

Rap2b RAP2B, member of RAS oncogene family

RAP2C RAP2C, member of RAS oncogene family

RAS1 GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes

RCN1 Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region

REL V-rel reticuloendotheliosis viral oncogene homolog (avian)

RELA V-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)

Rela V-rel reticuloendotheliosis viral oncogene homolog A (avian)

RELB V-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)

RET Ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)

Ret Ret proto-oncogene

RGD1305985_predicted Similar to H63 breast cancer expressed gene isoform a; gene associated with HER-2/neu overexpression (predicted)

RGD1306377_predicted Similar to prostate cancer antigen-1 (predicted)

RGD1306472_predicted Similar to leucine zipper, down-regulated in cancer 1; breast cancer, up-regulated 1 (predicted)

RGD1306945_predicted Similar to malignant cell expression-enhanced gene/tumor progression-enhanc (predicted)

RGD1307150_predicted Similar to Esophagus cancer-related gene-2 protein precursor (ECRG-2) (predicted)

RGD1308089_predicted Similar to common-site lymphoma leukemia guanine nucleotide exchange factor like (5N754) (predicted)

RGD1308257 Similar to intermediate filament-like protein MGC:2625 isoform 2; HOM-TES-103 tumor antigen-like

RGD1308331_predicted Similar to Trithorax homolog 2 (Mixed lineage leukemia gene homolog 2 protein) (predicted)

RGD1310112_predicted Similar to common-site lymphoma/leukemia GEF (predicted)

RGD1310591_predicted Similar to cervical cancer receptor (predicted)

RGD1310624_predicted Similar to chronic myelogenous leukemia tumor antigen 66 (predicted)

RGD1311474 Similar to transmembrane protein induced by tumor necrosis factor alpha

RGD1311547 Similar to CGI-96 protein; gastric cancer antigen Zg14

RGD1311926_predicted Similar to lung cancer metastasis-related protein 1 (predicted)

RGD1559445_predicted Similar to bromo domain-containing protein disrupted in leukemia (predicted)

RGD1559992_predicted Similar to polycystic kidney disease 2 (predicted)

RGD1560020_predicted Similar to Myb proto-oncogene protein (C-myb) (predicted)

RGD1561041_predicted Similar to C1q and tumor necrosis factor related protein 2 (predicted)

RGD1561818_predicted Similar to Nance-Horan syndrome protein (predicted)

RGD1561942_predicted Similar to mutated in bladder cancer 1 (predicted)

RGD1562236_predicted Similar to breast cancer membrane protein 101 (predicted)

RGD1562478_predicted Similar to RAB17, member RAS oncogene family (predicted)

RGD1563824_predicted Similar to Wilms tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA splicing regulator female-lethal(2D) homolog) (predicted)

RGD1564182_predicted Similar to Cat eye syndrome critical region protein 2 (predicted)

RGD1564417_predicted Similar to tumor protein D53 (predicted)

RGD1564623_predicted Similar to candidate tumor suppressor OVCA2 (predicted)

RGD1564816_predicted Similar to Serologically defined colon cancer antigen 13 (predicted)

RGD1565168_predicted Similar to RAP2A, member of RAS oncogene family (predicted)

Rmt1 Mammary cancer associated protein RMT-1

RNQ1 [PIN(+)] [PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate

ROS1 V-ros UR2 sarcoma virus oncogene homolog 1 (avian)

Ros1 V-ros UR2 sarcoma virus oncogene homolog 1 (avian)

RRAD Ras-related associated with diabetes

Rrad Ras-related associated with diabetes

RRAS Related RAS viral (r-ras) oncogene homolog

RRAS2 Related RAS viral (r-ras) oncogene homolog 2

Rras2 Related RAS viral (r-ras) oncogene homolog 2

Rras_predicted Harvey rat sarcoma oncogene, subgroup R (predicted)

RRS1 Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; mouse homolog shows altered expression in Huntington's disease model mice

Rsb30 RAB30, member RAS oncogene family

RTDR1 Rhabdoid tumor deletion region gene 1

RUNX1 Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)

SAK1 PAK1 Upstream kinase for the SNF1 complex; partially redundant function with Elm1p and Tos3p; members of this family of kinases have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome

SAS3 Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality

SBDS Shwachman-Bodian-Diamond syndrome

Sbds Shwachman-Bodian-Diamond syndrome

SCN5A Sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)

SCNN1B Sodium channel, nonvoltage-gated 1, beta (Liddle syndrome)

SDCCAG1 Serologically defined colon cancer antigen 1

SDCCAG10 Serologically defined colon cancer antigen 10

Sdccag10 Serologically defined colon cancer antigen 10

SDCCAG3 Serologically defined colon cancer antigen 3

SDCCAG33 Serologically defined colon cancer antigen 33

SDCCAG8 Serologically defined colon cancer antigen 8

SDO1 Essential protein involved in RNA metabolism, one of two yeast homologs (with Yhr087wp) of the human protein SBDS responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome, also conserved in Archaea

SE57-1 CTCL tumor antigen se57-1

SET SET translocation (myeloid leukemia-associated)

SGD1 Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia

SGS1 Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes

SH2D1A SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)

SKI V-ski sarcoma viral oncogene homolog (avian)

Slc22a18 Tumor suppressing subtransferable candidate 5

SLC25A16 Solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16

Slc7a5 Tumor-associated protein 1

SMCR7 Smith-Magenis syndrome chromosome region, candidate 7

SNCG Synuclein, gamma (breast cancer-specific protein 1)

SPG20 Spastic paraplegia 20, spartin (Troyer syndrome)

SPG21 Spastic paraplegia 21 (autosomal recessive, Mast syndrome)

SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1

Sprn Shadow of prion protein homolog (zebrafish)

Sprn Shadow of prion protein

SRC V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Src Rous sarcoma oncogene

SREBF1 Smith-Magenis syndrome chromosome region, candidate 3

SRO7 SNI1|SOP1 Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p

SRO77 SNI2|SOP2 Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p

SSB Sjogren syndrome antigen B (autoantigen La)

Ssb Sjogren syndrome antigen B

SSNA1 Sjogren's syndrome nuclear autoantigen 1

Ssna1_predicted Sjogren's syndrome nuclear autoantigen 1 (predicted)

SSPN Sarcospan (Kras oncogene-associated gene)

SSSCA1 Sjogren's syndrome/scleroderma autoantigen 1

ST13 Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)

St13 Suppression of tumorigenicity 13

ST14 Suppression of tumorigenicity 14 (colon carcinoma)

St14 Suppression of tumorigenicity 14

ST18 Suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)

St18 Suppression of tumorigenicity 18

ST5 Suppression of tumorigenicity 5

St5_predicted Suppression of tumorigenicity 5 (predicted)

ST7 Suppression of tumorigenicity 7

ST7L Suppression of tumorigenicity 7 like

STK22B DiGeorge syndrome critical region gene 13

STP22 VPS23 Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype

SUP35 GST1|PNM2|SAL3|SUF12|SUP2|SUP36|[PSI(+)]|[PSI]|eRF3 Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonse

TACSTD1 Tumor-associated calcium signal transducer 1

Tacstd1 Tumor-associated calcium signal transducer 1

TACSTD2 Tumor-associated calcium signal transducer 2

Tacstd2 Tumor-associated calcium signal transducer 2

TAL1 T-cell acute lymphocytic leukemia 1

TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1

Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1

TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3

Tax1bp3 Tax1 (human T-cell leukemia virus type I) binding protein 3

TAZ Tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)

TAZ1 Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; similar to human tafazzin, which is implicated in Barth syndrome

Taz_mapped Tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) (mapped)

TBX3 T-box 3 (ulnar mammary syndrome)

TCL1A T-cell leukemia/lymphoma 1A

TCL1B T-cell leukemia/lymphoma 1B

TCL6 T-cell leukemia/lymphoma 6

TCOF1 Treacher Collins-Franceschetti syndrome 1

Tcof1_predicted Treacher Collins Franceschetti syndrome 1, homolog (predicted)

TCTA T-cell leukemia translocation altered gene

Tde1 Tumor differentially expressed 1

Tde2 Tumor differentially expressed 1, like

TEP1 Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation

TFF1 Trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)

TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)

TGFB1 Transforming growth factor, beta 1 (Camurati-Engelmann disease)

THPO Thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor)

THRA Thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)

THRB Thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)

TIM8 Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; homolog of human DDP1 (deafness dystonia peptide 1) which is mutated in the X-linked Mohr-Tranebjaerg syndrome

TKT Transketolase (Wernicke-Korsakoff syndrome)

TLX1 T-cell leukemia, homeobox 1

TLX2 T-cell leukemia, homeobox 2

TLX3 T-cell leukemia, homeobox 3

TMA19 RBF18 Protein of unknown function; putative ribosomal protein; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YKL056C is not an essential gene

TMPIT Transmembrane protein induced by tumor necrosis factor alpha

TNF Tumor necrosis factor (TNF superfamily, member 2)

Tnf Tumor necrosis factor superfamily, member 2

TNFAIP1 Tumor necrosis factor, alpha-induced protein 1 (endothelial)

Tnfaip1 Tumor necrosis factor, alpha-induced protein 1 (endothelial)

TNFAIP2 Tumor necrosis factor, alpha-induced protein 2

TNFAIP3 Tumor necrosis factor, alpha-induced protein 3

TNFAIP6 Tumor necrosis factor, alpha-induced protein 6

TNFAIP8 Tumor necrosis factor, alpha-induced protein 8

TNFRSF10A Tumor necrosis factor receptor superfamily, member 10a

TNFRSF10B Tumor necrosis factor receptor superfamily, member 10b

TNFRSF10C Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

TNFRSF10D Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

TNFRSF11A Tumor necrosis factor receptor superfamily, member 11a, NFKB activator

TNFRSF11B Tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

TNFRSF12A Tumor necrosis factor receptor superfamily, member 12A

Tnfrsf12a Tumor necrosis factor receptor superfamily, member 12a

TNFRSF13B Tumor necrosis factor receptor superfamily, member 13B

TNFRSF14 Tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

Tnfrsf14 Tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

TNFRSF17 Tumor necrosis factor receptor superfamily, member 17

TNFRSF18 Tumor necrosis factor receptor superfamily, member 18

TNFRSF19 Tumor necrosis factor receptor superfamily, member 19

TNFRSF19L Tumor necrosis factor receptor superfamily, member 19-like

TNFRSF1A Tumor necrosis factor receptor superfamily, member 1A

Tnfrsf1a Tumor necrosis factor receptor superfamily, member 1a

TNFRSF1B Tumor necrosis factor receptor superfamily, member 1B

TNFRSF21 Tumor necrosis factor receptor superfamily, member 21

TNFRSF25 Tumor necrosis factor receptor superfamily, member 25

TNFRSF4 Tumor necrosis factor receptor superfamily, member 4

Tnfrsf4 Tumor necrosis factor receptor superfamily, member 4

Tnfrsf5 Tumor necrosis factor receptor superfamily, member 5

Tnfrsf6 Tumor necrosis factor receptor superfamily, member 6

TNFRSF6B Tumor necrosis factor receptor superfamily, member 6b, decoy

TNFRSF8 Tumor necrosis factor receptor superfamily, member 8

TNFRSF9 Tumor necrosis factor receptor superfamily, member 9

TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10

TNFSF11 Tumor necrosis factor (ligand) superfamily, member 11

Tnfsf11 Tumor necrosis factor (ligand) superfamily, member 11

Tnfsf12 Tumor necrosis factor ligand superfamily member 12

TNFSF13 Tumor necrosis factor (ligand) superfamily, member 12

Tnfsf13 Tumor necrosis factor (ligand) superfamily, member 13

TNFSF13B Tumor necrosis factor (ligand) superfamily, member 13b

TNFSF14 Tumor necrosis factor (ligand) superfamily, member 14

TNFSF15 Tumor necrosis factor (ligand) superfamily, member 15

TNFSF18 Tumor necrosis factor (ligand) superfamily, member 18

TNFSF4 Tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa)

Tnfsf4 Tumor necrosis factor (ligand) superfamily, member 4

Tnfsf5 Tumor necrosis factor (ligand) superfamily, member 5

TNFSF5IP1 Tumor necrosis factor superfamily, member 5-induced protein 1

Tnfsf5ip1_predicted Tumor necrosis factor superfamily, member 5-induced protein 1 (predicted)

Tnfsf6 Tumor necrosis factor (ligand) superfamily, member 6

TNFSF7 Tumor necrosis factor (ligand) superfamily, member 7

TNFSF8 Tumor necrosis factor (ligand) superfamily, member 8

TNFSF9 Tumor necrosis factor (ligand) superfamily, member 9

TOS3 Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome

TP53 Tumor protein p53 (Li-Fraumeni syndrome)

Tp53 Tumor protein p53

TP53BP1 Tumor protein p53 binding protein, 1

TP53BP2 Tumor protein p53 binding protein, 2

TP53I11 Tumor protein p53 inducible protein 11

Tp53i11_predicted Tumor protein p53 inducible protein 11 (predicted)

TP53I3 Tumor protein p53 inducible protein 3

TP53INP1 Tumor protein p53 inducible nuclear protein 1

TP53INP2 Tumor protein p53 inducible nuclear protein 2

TP73 Tumor protein p73

TP73L Tumor protein p73-like

TPD52 Tumor protein D52

TPD52L1 Tumor protein D52-like 1

TPD52L2 Tumor protein D52-like 2

Tpd52l2 Tumor protein D52-like 2

TPR Translocated promoter region (to activated MET oncogene)

TPT1 Tumor protein, translationally-controlled 1

Tpt1 Tumor protein, translationally-controlled 1

TRA1 Tumor rejection antigen (gp96) 1

Tra1_predicted Tumor rejection antigen gp96 (predicted)

Trap1 Tumor necrosis factor type 1 receptor associated protein

Trp53inp2 Tumor protein p53 inducible nuclear protein 2

TRPS1 Trichorhinophalangeal syndrome I

TRZ1 tRNase Z, involved in RNA processing, has two putative nucleotide triphosphate-binding motifs (P-loop) and a conserved histidine motif, homolog of the human candidate prostate cancer susceptibility gene ELAC2

TSG101 Tumor susceptibility gene 101

Tsg101 Tumor susceptibility gene 101

TSSC1 Tumor suppressing subtransferable candidate 1

TSSC4 Tumor suppressing subtransferable candidate 4

Tssc4 Tumor-suppressing subchromosomal transferable fragment 4

TUSC2 Tumor suppressor candidate 2

TUSC3 Tumor suppressor candidate 3

TUSC4 Tumor suppressor candidate 4

Tusc4 Tumor suppressor candidate 4

TUSC5 Tumor suppressor candidate 5

Tusc5 Tumor suppressor candidate 5

TWIST1 Twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)

UBE3A Ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)

URE2 [URE3] Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion

USH1C Usher syndrome 1C (autosomal recessive, severe)

USH2A Usher syndrome 2A (autosomal recessive, mild)

USHBP1 Usher syndrome 1C binding protein 1

USP4 Ubiquitin specific peptidase 4 (proto-oncogene)

USP6 Ubiquitin specific peptidase 6 (Tre-2 oncogene)

VAV1 Vav 1 oncogene

Vav1 Vav 1 oncogene

VAV2 Vav 2 oncogene

Vav2_predicted Vav2 oncogene (predicted)

VAV3 Vav 3 oncogene

VHL Von Hippel-Lindau tumor suppressor

Vhl Von Hippel-Lindau syndrome homolog

VMD2 Vitelliform macular dystrophy 2 (Best disease, bestrophin)

VRP1 END5|MDP2|YLR337W Proline-rich, actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP)

WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia)

WASL Wiskott-Aldrich syndrome-like

WASPIP Wiskott-Aldrich syndrome protein interacting protein

Wbscr14 Williams-Beuren syndrome chromosome region 14 homolog (human)

WBSCR16 Williams-Beuren syndrome chromosome region 16

Wbscr16_predicted Williams-Beuren syndrome chromosome region 16 (predicted)

WBSCR17 Williams-Beuren syndrome chromosome region 17

WBSCR18 Williams Beuren syndrome chromosome region 18

WBSCR20B Williams-Beuren Syndrome critical region protein 20 copy B

WBSCR20C Williams Beuren syndrome chromosome region 20C

WBSCR22 Williams Beuren syndrome chromosome region 22

WBSCR23 Williams-Beuren syndrome chromosome region 23

WBSCR27 Williams Beuren syndrome chromosome region 27

WBSCR28 Williams-Beuren syndrome critical region 28

WFS1 Wolfram syndrome 1 (wolframin)

Wfs1 Wolfram syndrome 1

WHSC1 Wolf-Hirschhorn syndrome candidate 1

WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1

WHSC2 Wolf-Hirschhorn syndrome candidate 2

Whsc2 Wolf-Hirschhorn syndrome candidate 2

WIT-1 Wilms tumor upstream neighbor 1

WRN Werner syndrome

WT1 Wilms tumor 1

Wt1 Wilms tumor 1

WTAP Wilms tumor 1 associated protein

WTIP Wilms tumor 1 interacting protein

YES1 V-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Yes1 Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

YHC3 BTN1 Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis)

YLH47 Mitochondrial inner membrane protein exposed to the mitochondrial matrix, associates with mitochondrial ribosomes, NOT required for respiratory growth; homolog of human Letm1, a protein implicated in Wolf-Hirschhorn syndrome

YNG1 YOR29-15 Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; has similarity to the human tumor suppressor ING1

YNG2 EAF4|NBN1 Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1

Zbp1 Tumor stroma and activated macrophage protein DLM-1