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Cytogenetics Database CytoD 1.0

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Query: t(1;19)(q23;p13.3)

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t(1;19)(q23;p13.3)     Fifteen cases of t(1;19)(q23;p13.3) identified in an Australian series of 122 children and 80 adults with acute lymphoblastic leukemia. Cancer Genet Cytogenet. 2001 Jan 15;124(2):132-6.
t(1;19)(q23;p13.3)     A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell. 1990 Feb 23;60(4):547-55.
t(1;19)(q23;p13.3)     Cytogenetic features and serum lactic dehydrogenase level predict a poor treatment outcome for children with pre-B-cell leukemia. Blood. 1986 Jun;67(6):1688-92.
t(1;19)(q23;p13.3)     Childhood acute lymphoblastic leukemia with both t(1;19) and t(9;22). Leukemia. 1992 Jun;6(6):535-40.
t(1;19)(q23;p13.3)     Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. Mol Cell Biol. 1994 Jun;14(6):3938-48.
t(1;19)(q23;p13.3)     Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6061-5.
t(1;19)(q23;p13.3)     Hypodiploidy is associated with a poor prognosis in childhood acute lymphoblastic leukemia. Blood. 1987 Jul;70(1):247-53.

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